Design Principles and Analysis Techniques for HRQoL Clinical TrialsSAS, R, and SPSS examples realistically show how to implement methods Focusing on longitudinal studies, Design and Analysis of Qual……続きを見る
Mismeasurement of explanatory variables is a common hazard when using statistical modeling techniques, and particularly so in fields such as biostatistics and epidemiology where perceived risk facto……続きを見る
Bayesian analyses have made important inroads in modern clinical research due, in part, to the incorporation of the traditional tools of noninformative priors as well as the modern innovations of ad……続きを見る
Completely revised and updated, Pharmaceutical Experimental Design and Interpretation, Second Edition explains the major methods of experimental design and evaluation such as multivariate, sequentia……続きを見る
Nueva edición de "Bioestadística amigable, texto de referencia en la asignatura y fuertemente introducido en el mercado tras una trayectoria de casi 15 años que aborda el estudio de los procedimient……続きを見る
This 5th edition of this popular graduate textbook presents a balanced and comprehensive treatment of both time and frequency domain methods with accompanying theory. It includes numerous examples u……続きを見る
- Libro que se centra en enseñar a investigadores cómo elaborar los contenidos de sus artículos científicos y en conocer el desarrollo del proceso editorial, siguiendo unas directrices ampliamente a……続きを見る
La obra constituye una introducción intuitiva pero muy rigurosa a la estadística que rehúye formulismos e incluye analogías y recursos gráficos muy útiles. Se trata de un libro muy práctico que prop……続きを見る
En un estilo claro y atractivo, Cómo leer un artículo científico. Las bases de la medicina basada en la evidencia desmitifica la medicina basada en la evidencia y explica cómo evaluar críticamente l……続きを見る
This work provides descriptions, explanations and examples of the Bayesian approach to statistics, demonstrating the utility of Bayesian methods for analyzing real-world problems in the health scien……続きを見る
"Provides current models, tools, and examples for the formulation and evaluation of scientific hypotheses in causal terms. Introduces a new method of model parametritization. Illustrates structural ……続きを見る
Statistical Concepts and Applications in Clinical Medicine presents a unique, problem-oriented approach to using statistical methods in clinical medical practice through each stage of the clinical p……続きを見る
Carefully designed for use by clinical and pharmaceutical researchers and scientists, Handbook of Regression Analysis and Modeling explores statistical methods that have been adapted into biological……続きを見る
Randomised Response-Adaptive Designs in Clinical Trials presents methods for the randomised allocation of treatments to patients in sequential clinical trials. Emphasizing the practical application ……続きを見る
Many methods for analyzing clustered data exist, all with advantages and limitations in particular applications. Compiled from the contributions of leading specialists in the field, Topics in Modell……続きを見る
Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for each stage of pharmaceutical development to ensure……続きを見る
Showcasing a discussion of the experimental process and a review of basic statistics, this volume provides methodologies to identify general data distribution, skewness, and outliers. It features a ……続きを見る
Dynamical Biostatistical Models presents statistical models and methods for the analysis of longitudinal data. The book focuses on models for analyzing repeated measures of quantitative and qualitat……続きを見る
Continuing advances in biomedical research and statistical methods call for a constant stream of updated, cohesive accounts of new developments so that the methodologies can be properly implemented ……続きを見る
The components of variance is a notion essential to statisticians and quantitative research scientists working in a variety of fields, including the biological, genetic, health, industrial, and psyc……続きを見る
WINNER 2009 CHOICE AWARD OUTSTANDING ACADEMIC TITLE! Nanotechnology is no longer a subdiscipline of chemistry, engineering, or any other field. It represents the convergence of many fields, and ther……続きを見る
A technically precise yet clear presentation of modern sequential methodologies having immediate applications to practical problems in the real world, Applied Sequential Methodologies communicates i……続きを見る
How does the brain work? After a century of research, we still lack a coherent view of how neurons process signals and control our activities. But as the field of computational neuroscience continue……続きを見る
Using time-to-event analysis methodology requires careful definition of the event, censored observation, provision of adequate follow-up, number of events, and independence or "noninformativeness" o……続きを見る
As many biological products face losing their patents in the next decade, the pharmaceutical industry needs an abbreviated regulatory pathway for approval of biosimilar drug products, which are cost……続きを見る
The growth of the pharmaceutical industry over the past decade is astounding, but the impact of this growth on statistics is somewhat confusing. While software has made analysis easier and more effi……続きを見る
Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statis……続きを見る
The US Food and Drug Administration's Report to the Nation in 2004 and 2005 indicated that one of the top reasons for drug recall was that stability data did not support existing expiration dates. P……続きを見る
Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a……続きを見る
This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM ……続きを見る