Genetics 5

Almost daily we hear news stories, advertisements, and scientific reports that promise genetic medicine will make us live longer, enable doctors to identify and treat diseases before they start, and……続きを見る

Evolution and Medicine provides an accessible introduction to the new field of evolutionary medicine. Evolutionary concepts help explain why we remain vulnerable to disease, how pathogens and cancer……続きを見る

Advances in genetic technology will lead to novel legal challenges. This book identifies four potential genomic claims which may be articulated as novel negligence challenges. Each of these claims i……続きを見る

Nowadays, it is widely accepted that there is no single influence (be it nature or nurture) on cognitive development. Cognitive abilities emerge as a result of interactions between gene expression, ……続きを見る

Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA……続きを見る

The manner in which genetic research associated with addiction is conducted, interpreted and translated into clinical practice and policy initiatives raises important social, ethical and legal issue……続きを見る

Personalized healthcare is rapidly approaching the American health care treatment scene in 2013. As a seasoned healthcare professional and educator, in my view, this has been a long time coming. I h……続きを見る

The controversial topic of the technology of Pre-implantation Genetic Diagnosis, and the muddled approach to this subject adopted by the UK Parliament, is explored in detail in this volume. The auth……続きを見る

In the past four years, many genetic loci have been implicated for BMI from the outcomes of genome-wide association studies (GWAS), primarily in adults. Insulin-induced gene 2 (INSIG2) was the first……続きを見る

The ciliopathies are a group of rare diseases that often affect multiple systems within the body, and are caused by defects in the function or structure of cilia. When cilia go wrong, there are prof……続きを見る

J. B. S. Haldane (1892-1964) was one of the most brilliant of British scientists - and one of the most controversial. A trail-blazing geneticist and physiologist, who used himself as his own guinea-……続きを見る

This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. It is fully updated with much molecular, scre……続きを見る

This book presents the statistical aspects of designing, analyzing and interpreting the results of genome-wide association scans (GWAS studies) for genetic causes of disease using unrelated subjects……続きを見る

Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological geno……続きを見る

A Life Course Approach to Mental Disorders examines the interplay of social and biological factors in the production of a wide range of mental disorders throughout life, from the peri-natal period t……続きを見る

Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success……続きを見る

This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation o……続きを見る

The OMICs: Applications in Neuroscience summarizes the state of the art in high-throughput approaches (collectively known as 'OMICs') in neurology and neuroscience, and is of interest to both neurol……続きを見る

Bilan historique et génétique du syndrome de Down. La trisomie 21, habituellement nommée syndrome de Down, mais qui en toute équité historique devrait s’appeler syndrome de Seguin-Down-Lejeune, est ……続きを見る

Multiple Sclerosis (MS) is thought to affect almost 2.5 million people worldwide. With the arrival of several new MS drugs and increased availability of information on the internet, many people are ……続きを見る

The development of effective methods for the prediction of ontological annotations is an important goal in computational biology, yet evaluating their performance is difficult due to problems caused……続きを見る

Researchers commonly ask subjects to self-identify their race from a menu of preestablished options. Yet if race is a multidimensional, multilevel social construction, this has profound methodologic……続きを見る

"Gene Therapy for Cartilage and Bone Tissue Engineering" outlines the tissue engineering and possible applications of gene therapy in the field of biomedical engineering as well as basic principles ……続きを見る

Great progress has been made in genetics in recent years, with significant consequences for the field of reproductive genetics. The ability to identify genetic defects before implantation, to diagno……続きを見る

There’s no easier, faster, or more practical way to learn the really tough subjects Genetics Demystified offers an up-to-date, highly readable explanation of the basic principles of genetics, coveri……続きを見る

The emerging field of regenerative medicine has led to a paradigm shift in therapeutic procedures. Scientific discovery in stem cell biology and material sciences, as well as in genetics have result……続きを見る

The year 2012 marks the tenth anniversary of the announcement of the genome sequence of the human malaria parasite Plasmodium falciparum and that of its mosquito vector Anopheles. The genome sequenc……続きを見る

Through the use of dramatic narratives, The Drama of DNA brings to life the complexities raised by the application of genomic technologies to health care and diagnosis. This creative, pedagogical ap……続きを見る

Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrat……続きを見る

This second edition has been comprehensively updated to reflect current clinical practice and the latest technical developments, including pre-implantation genetic diagnosis, array CGH, QF-PCR, non-……続きを見る