In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular……続きを見る
Research over the years has demonstrated that free radicals mediated oxidative stress lies at the helm of almost all patho-physiological phenomena. These findings emphasize on the need to understand……続きを見る
The human foetus is separated from the maternal blood by the syncytiotrophoblast induced by endogeneous human retrovirus-encoded proteins. This barrier is a highly developed one, which suppors apica……続きを見る
Influenza continues to be an ongoing problem despite the existence of vaccines and drugs. Disease outbreaks can occur relatively quickly as witnessed with the recent emergence of the influenza virus……続きを見る
The human immune system is a complex network of tissues and organs dispersed throughout the body. Immunology, as one of the most rapidly evolving fields in bio〓medical research, has to date covered……続きを見る
出版社: Springer International Publishing
発売日: 2014年11月06日
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention……続きを見る
Abnormal expression of MHC class I molecules in malignant cells is a frequent occurrence that ranges from total loss of all class I antigens to partial loss of MHC specific haplotypes or alleles. Di……続きを見る
Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: in……続きを見る
Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reactio……続きを見る
This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal imm……続きを見る
Microbial cell wall structures play a significant role in maintaining cells’ shape, as protecting layers against harmful agents, in cell adhesion and in positive and negative biological activities w……続きを見る
出版社: Springer International Publishing
発売日: 2014年10月16日
Malaria remains an alarming emergency in developing countries. It is thus urgent to identify any parasite or host molecules that can serve as new affordable markers for early diagnosis of disease co……続きを見る
JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to e……続きを見る
This Brief describes the concept and realization of gene therapy for HIV from the unique historic perspective and insight of two pioneers of the clinical applications of stem cell gene therapy for H……続きを見る
This Brief concerns the influence of chemistry in the modern food and beverages industry. The world of traditional foods has been soundlessly but increasingly interconnected with the chemical indust……続きを見る
This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal ……続きを見る
This volume offers an analysis of the scale and nature of the immunological issues facing regenerative medicine, drawing on the expertise of laboratories around the world who have taken up the chall……続きを見る
Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extract……続きを見る
Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and cro……続きを見る
This next volume in the series will provide up to date Information and discussion on future approach to control several challenging Infectious Disease worldwide. The past decade has been highlighted……続きを見る
出版社: Springer International Publishing
発売日: 2016年03月18日
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular……続きを見る
Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell……続きを見る
著者:Anna Kuchment
出版社: Springer New York
発売日: 2011年12月10日
Before the arrival of penicillin in the 1940s, phage therapy was one of the few weapons doctors had against bacterial infections. It saved the life of Hollywood legend Tom Mix before being abandoned……続きを見る
As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and……続きを見る
Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital l……続きを見る
Legionnaires’ disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. T……続きを見る
出版社: Springer International Publishing
発売日: 2014年09月02日
Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to unde……続きを見る
This volume throws light on the Sick Building Syndrome in Libraries and other public buildings, and the extent to which it is influenced by the internal environment of libraries. One of the signs of……続きを見る