The introduction of anti-tumour necrosis factor (TNF) antibodies into the treatment of patients with IBD about fifteen years ago has dramatically improved the quality of life for patients with sever……続きを見る
Despite decades of attention on building a global HIV research and programming agenda, HIV in older populations has generally been neglected until recently. This new book focuses on HIV and aging in……続きを見る
Many infectious diseases are more frequent and are associated with high morbidity and mortality in older adults. Vaccination is the most efficient strategy to prevent infections, and older adults ar……続きを見る
Over the past ten years tremendous progress has been achieved in corneal surgery. This volume – the 6th in the 'ESASO Course Series' – reflects the most relevant topics ranging from basic knowledge ……続きを見る
In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Po……続きを見る
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, che……続きを見る
Transboundary animal diseases (TADs) are a major threat to livestock. They are highly contagious or transmissible, and they have the potential to cause high morbidity and mortality in both susceptib……続きを見る
At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters i……続きを見る
Allergy and allergic diseases have increased in prevalence worldwide during the last decade. Relevant determinants influencing the development of allergic inflammation come from the environment and ……続きを見る
Ten years ago, the first edition of Graves’ Orbitopathy: A Multidisciplinary Approach was published. Since then, the book has become very popular and much has happened in the field to warrant a thir……続きを見る
The intestinal microbiome is especially important during the first thousand days of life. Exposure to microbes in utero significantly impacts fetal development, in part through epigenetic processes ……続きを見る
Vitamin D deficiency is prevalent today not only among the elderly but pervasively throughout all ages of life.This is due, in part, to systemic diseases that affect vitamin D metabolism, to changes……続きを見る
Neuroblastoma is a tumor derived from the sympathetic nervous system. It is the most common extracranial solid tumor occurring in children and exhibits a marked variability in outcome when the disea……続きを見る
Uveitis is a potentially blinding inflammatory disease that presents one of the most serious and complicated therapeutic challenges in the field of ophthalmology. During the last decade, the therape……続きを見る
Our understanding of the complex innate immune response is increasing rapidly. Its role in the protection against viral or bacterial pathogens is essential for the survival of an organism. However, ……続きを見る
In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlyin……続きを見る
In recent decades, it has become increasingly clear that the immune and nervous systems communicate with each other in a bidirectional way. The role of chronic stress in allergic disease and inflamm……続きを見る
Research into perspiration has developed dramatically during the last 15 years, continually improving our understanding of the pathogenesis of sweating disorders. It has become clear that, in additi……続きを見る
This volume is dedicated to the 70th anniversary of the Department of Otolaryngology of the Sapporo Medical University. It commemorates this landmark event and honors the department’s rich tradition……続きを見る
While first accounts of food allergy date back to antiquity, only in recent years has food allergy become recognized as one of the major allergic diseases. During the last decade the output of resea……続きを見る
With about 10–20% of the adult population in Europe being tattooed, there is a strong demand for publications discussing the various issues related to tattooed skin and health. Until now, only a few……続きを見る
This volume, written by renowned experts, provides complete coverage of the main genetic conditions associated with diabetes. Divided into five sections, it offers insights into genetic defects invo……続きを見る
Since ancient times the mistletoe plant has been used for healing diseases. Today mistletoe extract therapy is among the most thoroughly studied complementary treatments in Europe. Several studies a……続きを見る
Chronic kidney disease is a global major health issue that ultimately leads to end-stage renal disease, a devastating condition requiring costly renal replacement therapy. Given this background, ext……続きを見る
The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been ref……続きを見る
Human papillomavirus (HPV) infection transcends multiple fields of science and medicine. The management of HPV-related disease is demanding and often requires a persistent multimodal approach involv……続きを見る
After years of stagnation, much has been happening in the diagnosis and treatment of kidney diseases. This book contains a comprehensive review of the main developments in AKI, CKD, hemodialysis and……続きを見る
Gender medicine is an important new field in health and disease. It is derived from top-quality research and encompasses the biological and social determinants that underlie the susceptibility to di……続きを見る
Angiogenesis, the formation of new blood vessels, is fundamental for physiological processes such as embryonic and postnatal development, wound repair, and reproductive functions. Angiogenesis plays……続きを見る
Disorders associated with cortisol excess and insufficiency, although rare, deserve the attention of the entire medical community because of high associated morbidity and mortality. Both diagnosis a……続きを見る
