Biological Sciences 82

Sleep is a necessary, active, diverse and periodic condition, homeostatically regulated and precisely meshed with waking time into the sleep-wakefulness cycle. The authors present a detailed and upd……続きを見る

Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage a……続きを見る

The ?eld of cellular responses to DNA damage has attained widespread recognition and interest in recent years commensurate with its fundamental role in the ma- tenance of genomic stability. These re……続きを見る

Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently av……続きを見る

In 2001, first reports of the human draft genome were published. Since then, genomes of many other organisms have been sequenced, including several primate species: the chimpanzee, rhesus macaque, g……続きを見る

It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tum……続きを見る

Neuropsychological research on the neural basis of behavior generally asserts that brain mechanisms ultimately suffice to explain all psychologically described phenomena. This assumption stems from ……続きを見る

Axons are neuronal output elements and are responsible for the transfer and processing of signals from one neuron to another, even over very large distances. For a given neuronal cell type, axons ar……続きを見る

This study on the human midbrain examines how specific neuroanatomical structures are involved in the aging process and in certain degenerative diseases of the nervous system. 続きを見る

Immunocytochemistry of plant cells is the first book exclusively dedicated to this topic. The first and largest portion of the book is concerned with a group of proven protocols and variations on th……続きを見る

Population Aging: The Transformation of Societies presents an overview and international comparison of the causes, consequences and policy implications of one of the major processes of change in con……続きを見る

DNA Tumor Viruses will focus on the DNA viruses in the human population that are associated with cancers. 続きを見る

The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is bec……続きを見る

Tinnitus is a prevalent hearing disease, affecting 15% of the population, particularly hearing impaired, veterans and even young people who grow up with mp3 players and iPods. The mechanisms underly……続きを見る

Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in ……続きを見る

The present dire economic environment has greatly affected business and the opportunities for advancement or even holding a job. Even universities, although not directly in business, are feeling the……続きを見る

As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New resea……続きを見る

Various aspects, including diagnosis, therapy, and prognosis, of two brain tumors (meningioma and schwannoma) , of brain tumors are discussed in this volume. Insights on the understanding of molecul……続きを見る

Do real stem cells and stem cell lineages exist in lower organisms? Can stem cells from one organism parasitize the soma and/or the germ line of conspecifics? Can differentiated cells in marine orga……続きを見る

Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. The dynamic-clamp (also called “conductance injection”) allows experimen……続きを見る

Exploration and play behaviour form the subject of this book, in which a wide range of research activities, both theoretical and practical, are presented from various fields. In particular, the emph……続きを見る

Due to the current revolution in brain research the search for the “moral brain” became a serious endeavour. Nowadays, neural circuits that are indispensable for moral and social behaviour are disco……続きを見る

Using a combined morpho-functional approach the author recently found that polyinnervation of the neuro-muscular juction (NMJ) is the critical factor for recovery of function after transection and s……続きを見る

With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth ……続きを見る

view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The ……続きを見る

Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones hav……続きを見る

The aim of this book is not to encourage defensive medical practice, but to help provide better, optimum care to patients and to be forth right and honest to our dear customers about our inevitable ……続きを見る

Anyone who claims the right ‘to choose how to live their life’ excludes any purely deterministic description of their brain in terms of genes, chemicals or environmental influences. For example, whe……続きを見る

The Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic a……続きを見る

Presented in an interesting, historical and philosophical way, this book describes the current state of play in brain imaging, showing the differences among the different imaging modalities, and rev……続きを見る